ResoSens bioassay system

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RSI microarray plates specification sheet - Click Here

View the ResoSens bioassay system
specification sheet - Click Here

The ResoSens bioassay system can help speed up your cell-based and biochemical assays by eliminating the need for chemical labels and labor-intensive processing.

The system utilizes 96-well and 384-well Bionetic microarray plates that are integrated with advanced label-free optical sensor technology.

The ResoSens system provides dynamic monitoring of binding interactions throughout your entire experiment (as shown in Figure 1) – not just endpoint data.

Our information-rich data provides kinetic binding profiles and the ability to customize your assay to reduce testing time and increase throughput.

Figure 1.  Analysis of various concentrations of staphylococcal enterotoxin B detected in PBS.

Figure 1. Analysis of various concentrations of staphylococcal enterotoxin B detected in PBS.

Our innovative label-free approach is based on our proprietary guided-mode resonance sensor technology. High resolution monitoring of biochemical interactions are monitored using reflected light off the Bionetic microarray plate base. The surface of the Bionetic plate is nanostructured and designed to reflect a particular wavelength of light at a specific angle (Figure 2a). A wavelength shift occurs (Figure 2b) during the biochemical interaction – and the results are displayed in real-time on the screen.

Figure 2.  (a) Schematic of a guided-mode resonance sensor. The optical resonant modes are two different polarizations of light that are excited on the sensor surface and used to probe the binding reactions.

Figure 2. (a) Schematic of a guided-mode resonance sensor. The optical resonant modes are two different polarizations of light that are excited on the sensor surface and used to probe the binding reactions.

Figure 2. (b) Binding events occurring at the sensor surface produce resonance-peak shifts that can be tracked in real time.

Figure 2. (b) Binding events occurring at the sensor surface
produce resonance-peak shifts that can be tracked in real time.

Learn more about our technology and unique attributes – contact us for technical papers or speak to an RSI engineer.

Key applications include protein interaction monitoring, cell-based assays, and many others.

Features

  • 96- and 384- well disposable microarray formats
  • Results can be obtained for concentration analysis, kinetic characterization and qualification
  • Comprehensive customer support including PhD level assay development specialists to help you transition your assays to our instrument
  • Dynamic monitoring and real-time display of results during experiment
  • ResoVu analysis software provides statistical analysis/reporting or user can export data file for customized analysis
  • Ability to screen a full plate in about a minute
  • Ability to integrate with plate stacker and dispensing equipment for multiple plate analysis
  • 21 CFR Part 11 quality compliant software available as an upgrade

click to download: ResoSens bioassay system Spec Sheet

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